Invention Grant
- Patent Title: Amido-substituted pyridotriazine derivatives useful as HIV integrase inhibitors
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Application No.: US15775966Application Date: 2016-11-11
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Publication No.: US10548910B2Publication Date: 2020-02-04
- Inventor: Thomas H. Graham , Tao Yu , Sherman T. Waddell , John A. McCauley , Andrew Stamford , Wensheng Liu , Jay A. Grobler , Libo Xu
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; John C. Todaro
- International Application: PCT/US2016/061456 WO 20161111
- International Announcement: WO2017/087257 WO 20170526
- Main IPC: A61K31/675
- IPC: A61K31/675 ; A61P31/18 ; A61K31/683 ; A61K31/34 ; A61K31/426 ; A61K31/44 ; A61K31/513 ; A61K31/52 ; A61K31/535 ; A61K31/7068
Abstract:
The present invention relates to Amido-Substituted Pyridotriazine Derivatives of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein B, X, Y, R, R1, R2 and R10 are as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Pyridotriazine Derivative, and methods of using the Amido-Substituted Pyridotriazine Derivatives for treating or preventing HIV infection in a subject.
Public/Granted literature
- US20180325927A1 Amido-Substituted Pyridotriazine Derivatives Useful As HIV Integrase Inhibitors Public/Granted day:2018-11-15
Information query
