Invention Grant
- Patent Title: Hemichannel extracellular-domain specific agents for treating sepsis
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Application No.: US15748776Application Date: 2016-08-03
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Publication No.: US10548949B2Publication Date: 2020-02-04
- Inventor: Haichao Wang , Wei Li , Kevin J. Tracey , Ping Wang
- Applicant: The Feinstein Institute for Medical Research
- Applicant Address: US NY Manhasset
- Assignee: The Feinstein Institutes for Medical Research
- Current Assignee: The Feinstein Institutes for Medical Research
- Current Assignee Address: US NY Manhasset
- Agency: Amster, Rothstein & Ebenstein LLP
- International Application: PCT/US2016/045284 WO 20160803
- International Announcement: WO2017/023997 WO 20170209
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K31/19 ; A61K31/22 ; A61K31/704 ; C07K16/18 ; A61P37/02 ; A61K38/00 ; A61P31/02
Abstract:
Methods of treating sepsis or endotoxemia in a subject comprising administering to the subject an amount of an antagonist of a Panx1 hemichannel protein or an amount of an antagonist of a Cx43 hemichannel protein.
Public/Granted literature
- US20190008921A1 HEMICHANNEL EXTRACELLULAR-DOMAIN SPECIFIC AGENTS FOR TREATING SEPSIS Public/Granted day:2019-01-10
Information query
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