A patient support system includes a patient support apparatus having a base frame and a patient support surface. A network includes one or more of such patient support systems and an associated computer device. The patient support system includes: at least one sensor configured to detect at least one patient characteristic; at least one light emitting device capable of emitting light in at least a first range of visible wavelengths; and a controller configured to: receive the or each output from the at least one sensor; determine a stage of sleep of a patient on the patient support surface; receive a wake-up signal; and after receipt of the wake-up signal, activate the or each light emitting device to emit light substantially only in the first range of visible wavelengths when the controller next determines that the patient is in a light stage of sleep. The associated computer device is configured to carry out a patient wake-up process.