Methods and apparatus for real time machine vision and point-cloud data analysis are provided, for remote sensing and vehicle control. Point cloud data can be analyzed via scalable, centralized, cloud computing systems for extraction of asset information and generation of semantic maps. Machine learning components can optimize data analysis mechanisms to improve asset and feature extraction from sensor data. Optimized data analysis mechanisms can be downloaded to vehicles for use in on-board systems analyzing vehicle sensor data. Semantic map data can be used locally in vehicles, along with onboard sensors, to derive precise vehicle localization and provide input to vehicle to control systems.