Invention Grant
- Patent Title: 2-phenyl-3H-imidazo[4,5-B]pyridine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity
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Application No.: US15545523Application Date: 2016-02-01
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Publication No.: US10550113B2Publication Date: 2020-02-04
- Inventor: Hakan Mellstedt , Styrbjorn Bystrom , Jan Vagberg , Elisabeth Olsson
- Applicant: Kancera AB
- Applicant Address: SE Solna
- Assignee: KANCERA AB
- Current Assignee: KANCERA AB
- Current Assignee Address: SE Solna
- Agency: Renner, Otto, Boisselle & Sklar, LLP
- Priority: EP15153394 20150202
- International Application: PCT/EP2016/052091 WO 20160201
- International Announcement: WO2016/124553 WO 20160811
- Main IPC: C07D471/04
- IPC: C07D471/04
![2-phenyl-3H-imidazo[4,5-B]pyridine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity](/abs-image/US/2020/02/04/US10550113B2/abs.jpg.150x150.jpg)
Abstract:
A compound of formula (I′) or (I″) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.
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