Invention Grant
- Patent Title: JAK inhibitors containing a 4-membered heterocyclic amide
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Application No.: US16511410Application Date: 2019-07-15
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Publication No.: US10550118B2Publication Date: 2020-02-04
- Inventor: Paul R. Fatheree , Gary E. L. Brandt , Cameron Smith , Steven D. E. Sullivan , Lori Jean Van Orden , Melanie A. Kleinschek , Glenn D. Crater
- Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
- Applicant Address: US CA South San Francisco
- Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah; Florence Jovic
- Main IPC: A61P11/00
- IPC: A61P11/00 ; A61P11/06 ; C07D471/04 ; C07D519/00

Abstract:
The invention provides compounds of formula (I): which contain a 4-membered heterocyclic amide, where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat respiratory diseases, and processes and intermediates useful for preparing such compounds.
Public/Granted literature
- US20190337945A1 JAK INHIBITORS CONTAINING A 4-MEMBERED HETEROCYCLIC AMIDE Public/Granted day:2019-11-07
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