Invention Grant
- Patent Title: Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes
-
Application No.: US16484124Application Date: 2018-02-02
-
Publication No.: US10550127B1Publication Date: 2020-02-04
- Inventor: Matthias Eckhardt , Holger Wagner , Stefan Peters
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent David L. Kershner
- Priority: EP17155191 20170208
- International Application: PCT/EP2018/052620 WO 20180202
- International Announcement: WO2018/146008 WO 20180816
- Main IPC: C07D491/048
- IPC: C07D491/048 ; A61K45/06

Abstract:
The present invention relates to compounds of general formula I, wherein the groups R, R1, R2, m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
Public/Granted literature
Information query