Invention Grant
- Patent Title: Serpin reactive center loop peptides and methods of use
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Application No.: US15559867Application Date: 2016-03-18
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Publication No.: US10550172B2Publication Date: 2020-02-04
- Inventor: Alexandra Rose Lucas
- Applicant: University of Florida Research Foundation, Incorporated
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee Address: US FL Gainesville
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2016/023234 WO 20160318
- International Announcement: WO2016/154041 WO 20160929
- Main IPC: A61K38/07
- IPC: A61K38/07 ; A61K38/08 ; A61K38/10 ; A61K38/55 ; C07K5/11 ; C07K7/06 ; C07K7/08 ; C07K14/81 ; A61P31/22 ; A61P29/00 ; A61K9/00 ; A61K38/00
Abstract:
Disclosed here are peptides derived from a serpin reactive center loop that have anti¬inflammatory, anti-atherogenic and anti-sepsis activity. Compositions containing such serpin-derived peptides are therefore useful in the treatment of transplant vascular disease and also for the treatment of hemorrhagic viral infections as well as lethal viral, fungal or bacterial sepsis in patients.
Public/Granted literature
- US20180319868A1 SERPIN REACTIVE CENTER LOOP PEPTIDES AND METHODS OF USE Public/Granted day:2018-11-08
Information query
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