Invention Grant
- Patent Title: Bispecific heterodimeric fusion proteins containing IL-15-IL-15Rα Fc-fusion proteins and PD-1 antibody fragments
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Application No.: US15785393Application Date: 2017-10-16
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Publication No.: US10550185B2Publication Date: 2020-02-04
- Inventor: Matthew Bernett , Rumana Rashid , John Desjarlais , Rajat Varma , Christine Bonzon
- Applicant: Xencor, Inc.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Jennifer K. Ng; Robin M. Silva
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/54 ; C12N15/63 ; A61P35/00 ; C07K14/715 ; A61K35/00 ; A61K38/00 ; A61K39/00

Abstract:
The present invention is directed to novel bispecific heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc-fusion protein and a PD-1 antibody fragment-Fc fusion protein.
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