Invention Grant
- Patent Title: Integral membrane protein display on poxvirus extracellular enveloped virions
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Application No.: US16384087Application Date: 2019-04-15
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Publication No.: US10550199B2Publication Date: 2020-02-04
- Inventor: Ernest S. Smith , Mark Paris , Maria G. M. Scrivens , Renee A. Kirk , Angelica A. Cornelison
- Applicant: Vaccinex, Inc.
- Applicant Address: US NY Rochester
- Assignee: Vaccinex, Inc.
- Current Assignee: Vaccinex, Inc.
- Current Assignee Address: US NY Rochester
- Main IPC: A61K39/285
- IPC: A61K39/285 ; C12N15/86 ; A61K39/00 ; C07K14/005 ; C12N7/02 ; C07K16/32 ; C07K14/705 ; C07K16/28 ; C07K14/72 ; C07K14/71 ; C07K16/08 ; C07K14/715
Abstract:
This disclosure provides compositions and methods for expressing and displaying isolated integral membrane proteins (IMPs) or fragments thereof in a native conformation for use in the screening, selecting, and identifying of antibodies or antibody-like molecules that bind to a target IMP of interest.
Public/Granted literature
- US20190276556A1 INTEGRAL MEMBRANE PROTEIN DISPLAY ON POXVIRUS EXTRACELLULAR ENVELOPED VIRIONS Public/Granted day:2019-09-12
Information query
