Invention Grant
- Patent Title: Method for diagnosing premature delivery in a pregnant woman
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Application No.: US15552896Application Date: 2016-02-19
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Publication No.: US10550442B2Publication Date: 2020-02-04
- Inventor: Yoon-Keun Kim , Young-Ju Kim , Young Koo Jee , Mina Rho , Byung-In Moon , Minhye Kim
- Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION , DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION
- Applicant Address: KR Seoul
- Assignee: MD HEALTHCARE INC.
- Current Assignee: MD HEALTHCARE INC.
- Current Assignee Address: KR Seoul
- Agency: Vorys, Sater, Seymour and Pease LLP
- Agent Mih Suhn Koh
- Priority: KR10-2015-0025381 20150223
- International Application: PCT/KR2016/001665 WO 20160219
- International Announcement: WO2016/137164 WO 20160901
- Main IPC: C12N9/96
- IPC: C12N9/96 ; C12R1/07 ; A61K35/74 ; C12N1/20 ; C12Q1/686 ; G01N33/574

Abstract:
Provided is a composition for the treatment of pregnancy-associated diseases, and more particularly, to a pharmaceutical composition for the prevention or treatment of premature delivery or breast cancer. The pharmaceutical composition including extracellular vesicles derived from bacteria belonging to the genus Bacillus as an active ingredient may induce pregnancy or prevent premature delivery of pregnant women, may be used to prevent or treat pregnancy-associated diseases such as breast cancer, and may be used to diagnose a risk of premature delivery by measuring the amount of extracellular vesicles derived from bacteria belonging to the genus Bacillus in pregnant women.
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