A device for sanitary collection of materials features a bag having a closed bottom end, side walls that extend from the closed bottom end to delimit a collection space above the closed bottom end, and a hand protector that is attached to one of said side walls and has a hollow interior that is open or openable at one end to enable insertion of one's hand into the hand protector. A handle is provided in an opposing side wall so that that bag can be suspended in an open state between a wrist or forearm on which the hand protector is worn, and the hand of the user's opposite arm. A stamping operation performed on a continuous plastic web is operable to efficiently create the bag and hand protector as integral parts of a unitary bag construction.