A scalable sensor calibration system and method configured to calibrate and/or recalibrate sensors based on calibration parameters received from secure cloud storage. A plurality of calibration parameter sets for a plurality of sensors may be received from the secure cloud storage and successively transmitted to each of the plurality of sensors using a calibration system bus interface. Calibration output data generated by the sensors using the calibration parameters is received and used to create new, optimized calibration parameters sets.