Invention Grant
- Patent Title: MTOR kinase mutations and methods of use thereof
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Application No.: US15482340Application Date: 2017-04-07
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Publication No.: US10551384B2Publication Date: 2020-02-04
- Inventor: Steven Zheng
- Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- Applicant Address: US NJ New Brunswick
- Assignee: Rutgers, The State University Of New Jersey
- Current Assignee: Rutgers, The State University Of New Jersey
- Current Assignee Address: US NJ New Brunswick
- Agency: Viksnins Harris Padys Malen LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/574 ; A61K31/5377 ; A61K31/495 ; A61K31/519 ; A61K31/4709 ; A61K31/4745 ; G01N33/50 ; C12Q1/6886 ; C12N9/12 ; A61K31/53
Abstract:
Certain embodiments of the invention provide a method of detecting the presence of a biomarker associated with resistance to an mTOR kinase inhibitor in a subject, comprising determining the presence of the biomarker in a physiological sample from the subject, wherein the sample comprises a nucleic acid.
Public/Granted literature
- US20170299596A1 MTOR KINASE MUTATIONS AND METHODS OF USE THEREOF Public/Granted day:2017-10-19
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