Systems and methods for determining placement of computing workloads within a network are disclosed. According to an aspect, a method includes determining one or more attributes of a computing workload to be placed within a network. The method also includes predicting interaction of the computing workload with one or more other computing workloads within the network based on the one or more attributes. Further, the method includes determining placement of the computing workload within the network based on the predicted interaction and a topology of the network.