Invention Grant
- Patent Title: Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
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Application No.: US16066921Application Date: 2017-01-04
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Publication No.: US10555934B2Publication Date: 2020-02-11
- Inventor: Patrick Naxos Page , Matthias Schwarz , Catherine Jorand-Lebrun , Anna Quattropani , Vincent Pomel , Ernest Loumaye , Oliver Pohl , Jean-Pierre Gotteland
- Applicant: ObsEva S.A.
- Applicant Address: CH Plan-les-Ouates
- Assignee: ObsEva S.A.
- Current Assignee: ObsEva S.A.
- Current Assignee Address: CH Plan-les-Ouates
- Agency: Clark & Elbing LLP
- International Application: PCT/EP2017/050099 WO 20170104
- International Announcement: WO2017/118639 WO 20170713
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61K45/06 ; A61P15/06 ; A61K9/00

Abstract:
The invention provides pharmaceutical compositions comprising a compound of formula (I) or (II) and an additional therapeutic agent Also provided is the HCI salt and crystalline form of the compound of formula (I). The compounds inhibit the prostaglandin F receptor (PGF2alpha) and thus useful in the treatment of disorders such as preterm labor at the early gestational stage.
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Information query
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