Invention Grant
- Patent Title: Lysosomal targeting of enzymes, and uses thereof
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Application No.: US15521130Application Date: 2015-10-23
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Publication No.: US10556015B2Publication Date: 2020-02-11
- Inventor: Bohong Zhang , Michael F. Concino
- Applicant: Shire Human Genetic Therapies, Inc.
- Applicant Address: FR Paris
- Assignee: Criteo S.A.
- Current Assignee: Criteo S.A.
- Current Assignee Address: FR Paris
- Agency: Proskauer Rose LLP
- Agent Fangli J. D. Chen; Julio J. Mendez
- International Application: PCT/US2015/057214 WO 20151023
- International Announcement: WO2016/065319 WO 20160428
- Main IPC: A61K47/65
- IPC: A61K47/65 ; C12N9/64 ; C12N9/24 ; A61K47/64 ; C12N9/96 ; C12N15/62
Abstract:
The invention provides compositions and methods for effective lysosomal targeting mediated by PCSK9. In particular, the compositions and methods provided by the invention may be used to treat lysosomal storage diseases such as Pompe Disease and Sanfilippo Syndrome Type B, and they may be used for targeting lysosomal enzymes to the various muscles of the human body.
Public/Granted literature
- US20170333569A1 LYSOSOMAL TARGETING OF ENZYMES, AND USES THEREOF Public/Granted day:2017-11-23
Information query
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