Invention Grant
- Patent Title: Nanocarriers for drug delivery
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Application No.: US15412912Application Date: 2017-01-23
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Publication No.: US10556021B2Publication Date: 2020-02-11
- Inventor: Kit S. Lam , Juntao Luo
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky & Popeo, P.C.
- Main IPC: A61K51/06
- IPC: A61K51/06 ; A61K49/00 ; A61K9/107 ; A61K9/51 ; B82Y5/00

Abstract:
The present invention provides a nanocarrier having an interior and an exterior, the nanocarrier comprising at least one conjugate, wherein each conjugate includes a polyethylene glycol (PEG) polymer. Each conjugate also includes at least two amphiphilic compounds having both a hydrophilic face and a hydrophobic face. In addition, each conjugate includes an oligomer, wherein at least 2 of the amphiphilic compounds are covalently attached to the oligomer which is covalently attached to the PEG. The nanocarrier is such that each conjugate self-assembles in an aqueous solvent to form the nanocarrier such that a hydrophobic pocket is formed in the interior of the nanocarrier by the orientation of the hydrophobic face of each amphiphilic compound towards each other, and wherein the PEG of each conjugate self-assembles on the exterior of the nanocarrier.
Public/Granted literature
- US20170290921A1 NANOCARRIERS FOR DRUG DELIVERY Public/Granted day:2017-10-12
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