A thermo-sealing machine for filling containers with liquids and sealing them, comprising a bearing structure on which a bell member is mounted, at a higher position than that of support means for supporting at least a container to be filled and sealed, said bell member comprising a metering device, die-cutting means and sealing means, for die-cutting and sealing a film slidable between said bell member and the container to be filled, said machine being provided with an anti-polluting and operator safety system.