Invention Grant
- Patent Title: Process for the purification of TNFR:Fc fusion protein
-
Application No.: US15318489Application Date: 2015-06-13
-
Publication No.: US10556942B2Publication Date: 2020-02-11
- Inventor: Abir Banerjee , Chandranath Ganapathy , Sorab Rustom Mody , Ashok Mishra
- Applicant: LUPIN LIMITED
- Applicant Address: IN Mumbai
- Assignee: LUPIN LIMITED
- Current Assignee: LUPIN LIMITED
- Current Assignee Address: IN Mumbai
- Agency: Duane Morris LLP
- Agent J. Rodman Steele, Jr.; Gregory M. Lefkowitz
- Priority: IN1919/MUM/2014 20140613
- International Application: PCT/IB2015/054494 WO 20150613
- International Announcement: WO2015/189832 WO 20151217
- Main IPC: C07K16/22
- IPC: C07K16/22 ; C07K1/18 ; C07K14/705 ; B01D15/12 ; B01D15/20 ; B01D15/30 ; B01D15/36 ; B01D15/38 ; B01D15/42
Abstract:
The present invention relates to the purification of TNFR:Fc fusion protein. More specifically related to process of purification of TNFR:Fc fusion protein wherein the HCP is reduced. The present invention is directed to the use of mixed-mode chromatography and/or affinity chromatography to produce TNFR:Fc fusion protein which is substantially free of at least one of the protein degrading enzyme present in HCP.
Public/Granted literature
- US20170152298A1 PROCESS FOR THE PURIFICATION OF TNFR:FC FUSION PROTEIN Public/Granted day:2017-06-01
Information query
