Invention Grant
- Patent Title: Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject
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Application No.: US16241017Application Date: 2019-01-07
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Publication No.: US10557118B2Publication Date: 2020-02-11
- Inventor: Richard William Wyatt Childs , Yoshiyuki Takahashi , Sachiko Kajigaya , Nanae Harashima
- Applicant: The Government of the USA, as represented by the Secretary, Dept. of Health and Human Services
- Applicant Address: US MD Bethseda
- Assignee: The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethseda
- Agency: Klarquist Sparkman, LLP
- Main IPC: C12N5/0783
- IPC: C12N5/0783 ; A61K39/21 ; C07K14/005 ; A61K39/12 ; A61K35/12 ; A61K35/17 ; A61K39/00
Abstract:
Compositions and methods are provided for preventing or treating neoplastic disease in a mammalian subject. A composition is provided which comprises an enriched immune cell population reactive to a human endogenous retrovirus type E antigen on a tumor cell. A method of treating a neoplastic disease in a mammalian subject is provided which comprises administering to a mammalian subject a composition comprising an enriched immune cell population reactive to a human endogenous retrovirus type E antigen, in an amount effective to reduce or eliminate the neoplastic disease or to prevent its occurrence or recurrence.
Public/Granted literature
- US20190127695A1 COMPOSITIONS AND METHODS FOR PREVENTION OR TREATMENT OF NEOPLASTIC DISEASE IN A MAMMALIAN SUBJECT Public/Granted day:2019-05-02
Information query
