Invention Grant
- Patent Title: Compositions and methods for obtaining stem cell derived lung tissue, and related uses thereof
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Application No.: US15134498Application Date: 2016-04-21
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Publication No.: US10557124B2Publication Date: 2020-02-11
- Inventor: Jason Spence , Briana Dye
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, SC
- Agent Robert Goetz
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
The invention disclosed herein generally relates to methods and systems for converting stem cells into specific tissue(s) or organ(s) through directed differentiation. In particular, the invention disclosed herein relates to methods and systems for promoting definitive endoderm formation from pluripotent stem cells. The invention disclosed herein further relates to methods and systems for promoting ventral-anterior foregut spheroid tissue formation, 3-dimensional lung tissue formation, and lung organoid tissue formation produced in vitro from the described methods.
Public/Granted literature
- US20160312191A1 COMPOSITIONS AND METHODS FOR OBTAINING STEM CELL DERIVED LUNG TISSUE, AND RELATED USES THEROF Public/Granted day:2016-10-27
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