• Patent Title: Peptides derived from human PCSK9 catalytic domain and uses thereof for promoting LDL-R activity
  • Application No.: US15547277
    Application Date: 2016-01-29
  • Publication No.: US10557129B2
    Publication Date: 2020-02-11
  • Inventor: Ajoy Basak
  • Applicant: Pronasci Inc.
  • Applicant Address: CA Montreal
  • Assignee: Pronasci inc.
  • Current Assignee: Pronasci inc.
  • Current Assignee Address: CA Montreal
  • Agency: Benoit & Cote, Inc.
  • Agent Mathieu Miron
  • International Application: PCT/CA2016/050080 WO 20160129
  • International Announcement: WO2016/119067 WO 20160804
  • Main IPC: C07K7/08
  • IPC: C07K7/08 C12N9/64 A61K38/48 A61K45/06
Peptides derived from human PCSK9 catalytic domain and uses thereof for promoting LDL-R activity
Abstract:
The present invention provides compositions comprising an isolated or purified therapeutically effective hPCSK9 polypeptide derived from the hPCSK9 catalytic domain, and their use in methods of treating hypercholesterolemia.
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