Invention Grant
- Patent Title: Transgenic bacteria with expanded amino acid usage and nucleic acid molecules for use in the same
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Application No.: US15380560Application Date: 2016-12-15
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Publication No.: US10557160B2Publication Date: 2020-02-11
- Inventor: Andrew D. Ellington , Ross Thyer
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12P21/02 ; C12N9/86 ; C12N9/00 ; C12N15/11
Abstract:
Recombinant bacterial cells are provided that comprise a stable non-canonical amino acid translation pathway. In some aspects, the bacteria comprise nucleic acids encoding a non-canonical amino acid translation pathway (e.g., a tRNA for incorporation of a non-canonical amino acid, such selenocysteine); a marker polypeptide that includes the non-canonical amino acid. Recombinant tRNA and selection marker coding sequences are likewise provided.
Public/Granted literature
- US20170166945A1 TRANSGENIC BACTERIA WITH EXPANDED AMINO ACID USAGE AND NUCLEIC ACID MOLECULES FOR USE IN THE SAME Public/Granted day:2017-06-15
Information query
