Invention Grant
- Patent Title: Local genetic ethnicity determination system
-
Application No.: US15209458Application Date: 2016-07-13
-
Publication No.: US10558930B2Publication Date: 2020-02-11
- Inventor: Keith D. Noto , Yong Wang
- Applicant: Ancestry.com DNA, LLC
- Applicant Address: US UT Lehi
- Assignee: Ancestry.com DNA, LLC
- Current Assignee: Ancestry.com DNA, LLC
- Current Assignee Address: US UT Lehi
- Agency: Fenwick & West LLP
- Main IPC: G06F19/00
- IPC: G06F19/00 ; G06N7/00

Abstract:
An input sample SNP genotype is divided into a plurality of windows, each including a sequence of SNPs. For each window, a diploid hidden Markov Model (HMM) is built and from a haplotype Markov Model (MM). The diploid HMM for a window is used to determine the probability that the window corresponds to a pair of labels (e.g., ethnicity labels). An inter-window HMM, with a set of states for each window, is built based on the diploid HMMs for each window. Labels are assigned to the input sample genotype based on the inter-window HMM.
Public/Granted literature
- US20170017752A1 LOCAL GENETIC ETHNICITY DETERMINATION SYSTEM Public/Granted day:2017-01-19
Information query