Invention Grant
- Patent Title: Solid preparation including antioxidant
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Application No.: US15559573Application Date: 2016-03-17
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Publication No.: US10561628B2Publication Date: 2020-02-18
- Inventor: Shinichiro Tajiri , Jin Hisazumi , Shinji Yoshinaga , Hiroyuki Fujimori , Hiroaki Arai
- Applicant: DAIICHI SANKYO COMPANY, LIMITED
- Applicant Address: JP Tokyo
- Assignee: DAIICHI SANKYO COMPANY, LIMITED
- Current Assignee: DAIICHI SANKYO COMPANY, LIMITED
- Current Assignee Address: JP Tokyo
- Agency: Dorsey & Whitney LLP
- Priority: JP2015-055768 20150319
- International Application: PCT/JP2016/058607 WO 20160317
- International Announcement: WO2016/148263 WO 20160922
- Main IPC: A61K31/195
- IPC: A61K31/195 ; A61K9/20 ; A61K9/28

Abstract:
An object of the present invention is to provide [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate as a stabilized pharmaceutical solid preparation, and also to provide a method for preparing the stabilized pharmaceutical solid preparation. The object can be attained by a pharmaceutical solid preparation comprising [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate which is a compound represented by the following formula (I) in combination with (i) one or two or more excipients, (ii) one or two or more disintegrants, and (iii) a specific antioxidant.
Public/Granted literature
- US20180042878A1 SOLID PREPARATION INCLUDING ANTIOXIDANT Public/Granted day:2018-02-15
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