Invention Grant
- Patent Title: Use of quinoline derivatives for treating oesophageal cancer and treatment method, pharmaceutical composition and kit thereof
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Application No.: US16068332Application Date: 2017-01-06
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Publication No.: US10561647B2Publication Date: 2020-02-18
- Inventor: Xunqiang Wang , Ling Yang , Zhongnan Xu , Xiangjian Wang , Wenjun Geng
- Applicant: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Applicant Address: CN Lianyungang
- Assignee: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Current Assignee: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Current Assignee Address: CN Lianyungang
- Agency: Nixon Peabody LLP
- Priority: CN201610013628 20160108
- International Application: PCT/CN2017/070352 WO 20170106
- International Announcement: WO2017/118401 WO 20170713
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61P35/00

Abstract:
Provided in the present invention are a use of quinoline derivatives for treating oesophageal cancer and a treatment method, a pharmaceutical composition and a kit thereof. The 1-[[[4-(4-fluoro-2-methyl-1H-indole-5-yl)oxy-6-methoxyquinoline-7-yl]oxy]methyl]cyclopropylamine provided by the present invention can effectively treat oesophageal cancer, and reduce the sum of the diameters of patient's target lesions.
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