Invention Grant
- Patent Title: Process for the preparation of 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones
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Application No.: US16089486Application Date: 2017-03-31
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Publication No.: US10562889B2Publication Date: 2020-02-18
- Inventor: Suixiong Cai , Ping Huang
- Applicant: IMPACT THERAPEUTICS, INC.
- Applicant Address: CN Shanghai
- Assignee: IMPACT THERAPEUTICS, INC.
- Current Assignee: IMPACT THERAPEUTICS, INC.
- Current Assignee Address: CN Shanghai
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: CN201610202881 20160401
- International Application: PCT/CN2017/078913 WO 20170331
- International Announcement: WO2017/167251 WO 20171005
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D239/96 ; B01D9/00

Abstract:
This disclosure provides a process for preparing 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones, specially provides a method for preparing the compound of Formula I, and the method comprises the step of reacting the compound of Formula II with the compound of Formula A in the presence of a condensation agent, an organic base and an organic solvent by condensation.
Public/Granted literature
- US20190112298A1 PROCESS FOR THE PREPARATION OF 1-(ARYLMETHYL)QUINAZOLINE-2,4(1H,3H)-DIONES Public/Granted day:2019-04-18
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