Invention Grant
- Patent Title: PIV5-based amplifying virus-like particles
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Application No.: US15556158Application Date: 2016-04-28
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Publication No.: US10563178B2Publication Date: 2020-02-18
- Inventor: Biao He
- Applicant: University of Georgia Research Foundation, Inc.
- Applicant Address: US GA Athens
- Assignee: University of Georgia Research Foundation, Inc.
- Current Assignee: University of Georgia Research Foundation, Inc.
- Current Assignee Address: US GA Athens
- Agency: Smith Gambrell & Russell LLP
- International Application: PCT/US2016/029884 WO 20160428
- International Announcement: WO2016/176510 WO 20161103
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K48/00 ; C07K14/005 ; C12N9/22 ; C12N15/11
Abstract:
Compositions, methods of use and methods of manufacture are provided for PIV5-based amplifying VLP (AVLP) that can deliver an expressible heterologous nucleotide sequence in target cells without producing progeny, and which demonstrate useful safety and therapeutic efficacy in multiple animal and human health applications, such as vaccination, gene therapy and cancer therapy.
Public/Granted literature
- US20180044644A1 PIV5-Based Amplifying Virus-Like Particles Public/Granted day:2018-02-15
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