Invention Grant
- Patent Title: Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
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Application No.: US15869549Application Date: 2018-01-12
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Publication No.: US10563183B2Publication Date: 2020-02-18
- Inventor: Erno Pungor , Charles Hague , Zhi Chen
- Applicant: BioMarin Pharmaceutical Inc.
- Applicant Address: US CA Novato
- Assignee: BioMarin Pharmaceutical Inc.
- Current Assignee: BioMarin Pharmaceutical Inc.
- Current Assignee Address: US CA Novato
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C12N9/16
- IPC: C12N9/16 ; C12Q1/34 ; C12Q1/44 ; G01N33/68 ; A61K38/00

Abstract:
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
Public/Granted literature
- US20180208913A1 Manufacture of Active Highly Phosphorylated Human Lysosomal Sulfatase Enzymes and Uses Thereof Public/Granted day:2018-07-26
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