Interactive sequential pattern mining is disclosed. One example is a system including a sequence miner, and an interaction processor. A sequence database is received, the sequence database including a plurality of input sequences, where each sequence of the plurality of input sequences is an ordered list of events, and each event in the list of events includes at least one item. The sequence miner mines the sequence database for a plurality of candidate sequence patterns, the mining based on an interaction with a user. The interaction processor processes the interaction with the user, the interaction based on domain relevance of the plurality of candidate sequence patterns to the user.