The invention discloses a power configuration structure and method for top-emitting AMOLED panel. The structure comprises: a plurality of VDD electrodes, for inputting a high voltage power source to AMOLED panel pixel driver circuit, and a transparent cathode, for inputting a low voltage power source to the AMOLED panel pixel driver circuit, the transparent cathode being prepared by a planar vapor deposition process, VSS power input points being disposed on two opposite sides of the transparent cathode; the plurality of VDD electrodes being arranged in parallel with a direction perpendicular to the VSS power input points, each VDD electrode having two ends disposed with VDD power input points. The invention also provides a corresponding power configuration method. The power configuration structure and method of the invention combines a 3T1C driver circuit to effectively relieve the IR voltage drop caused by impedance increase of the transparent cathode to improve display.