A segmented resistor string type digital to analog converter comprises: a most significant bit (MSB) resistor string (104) comprising a high level resistor string, an intermediate level resistor string and a ground level resistor string; a decoding circuit (101), configured to decode an n-bit code of the MSB resistor string (104) and output 2n decoded codes; a logic sequential generation circuit (102), connected to the decoding circuit (101) and configured to perform a logic operation on a middle-position code among the 2n decoded codes and a refresh clock signal in non-overlapping sequences, and output two groups of control signals with completely complementary high level durations; a control signal bootstrap circuit (103), connected to the logic sequential generation circuit (102) and configured to perform bootstrap processing on the control signal, and increase the high level of the control signal to a sum of a power supply voltage and a threshold voltage; and a first switch group (106), connected to the control signal bootstrap circuit (103) and the intermediate level resistor string, where on/off of the first switch group (106) is controlled by the control signal after the bootstrap processing, so as to connect the intermediate level resistor string to the circuit or disconnect the intermediate level resistor string from the circuit.