Embodiments of the present disclosure relate to autofocusing of images using motion vectors generated by an image signal processor of a device. An image being processed may include one or more motion detection windows associated with a motion vector as well as one or more autofocus windows. An autofocus window that follows a motion detection window by at least a threshold vertical distance may be selected, for example, to account for a period of time or latency for determining a motion vector of the motion detection window. The device may perform autofocusing by shifting location of the selected autofocus window.