A power switch circuit includes a first switch circuit, a second switch unit and a capacitor. The capacitor has a first terminal coupled to a node between the first and second switch units. In addition, the capacitor has a second terminal coupled to the first and second switch units, a charge pump and a charging circuit. When the power switch circuit is coupled to a load, the charging circuit pre-charges the capacitor. Once the load is enabled, the first and second switch units are turned on by only a small voltage increase at the second terminal of the capacitor by the charge pump to allow power to be supplied to a load through the first and second switch units from a power supply.