An article of footwear includes an upper, a midsole connected to the upper, and an outsole connected to the midsole. The midsole includes a lattice structure comprising a network of laths forming a plurality of cell units, the plurality of cell units arranged in a plurality of layers on the midsole. The midsole defines at least a first zone and a second zone wherein each cell unit in the first zone has a physical property that is substantially different from a cell unit in the second zone.