Invention Grant
- Patent Title: Neuroprotection by mitochondria-targeted metformin
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Application No.: US15963648Application Date: 2018-04-26
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Publication No.: US10576093B2Publication Date: 2020-03-03
- Inventor: Anumantha Kanthasamy , Balaraman Kalyanaraman
- Applicant: Iowa State University Research Foundation, Inc. , The Medical College of Wisconsin, Inc.
- Applicant Address: US IA Ames US WI Milwaukee
- Assignee: Iowa State University Research Foundation, Inc.,The Medical College of Wisconsin, Inc.
- Current Assignee: Iowa State University Research Foundation, Inc.,The Medical College of Wisconsin, Inc.
- Current Assignee Address: US IA Ames US WI Milwaukee
- Agency: Quarles & Brady LLP
- Main IPC: A61K31/662
- IPC: A61K31/662 ; A61K31/44 ; A61K31/4425
Abstract:
The present invention provides modified metformin compounds, particularly mito-metformin compounds, and pharmaceutical compositions thereof. Methods of using the compounds to provide neuroprotection and in the treatment and/or prevention of neurodegenerative diseases are also described.
Public/Granted literature
- US20190091245A1 Neuroprotection by mitochondria-targeted metformin Public/Granted day:2019-03-28
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