Invention Grant
- Patent Title: Immune conjugate having dendron conjugated to antibody and use thereof
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Application No.: US15795528Application Date: 2017-10-27
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Publication No.: US10576158B2Publication Date: 2020-03-03
- Inventor: Young Deug Kim , Eun Ji Park , Yejin Kim , Young Kee Shin , Jun Young Choi
- Applicant: ABION INC.
- Applicant Address: KR Seoul
- Assignee: ABION INC.
- Current Assignee: ABION INC.
- Current Assignee Address: KR Seoul
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Priority: KR10-2015-0059264 20150427
- Main IPC: A61K47/50
- IPC: A61K47/50 ; A61K47/68 ; C07K16/28 ; A61P35/00 ; C07K16/30 ; C08G83/00 ; A61K39/00
Abstract:
An immune conjugate according to the present invention provides a pharmaceutical composition, which can be used in the target-oriented drug treatment by conjugating a dendron allowing a plurality of drugs to be bound to a surface thereof and a target-directed antibody, and especially, can deliver high concentrations of drugs in a tumor-specific manner to exhibit a strong anticancer effect by conjugating a hydrophilic dendron, to which a plurality of anticancer drugs are bound, to an antibody.
Public/Granted literature
- US20180110860A1 IMMUNE CONJUGATE HAVING DENDRON CONJUGATED TO ANTIBODY AND USE THEREOF Public/Granted day:2018-04-26
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