Invention Grant
- Patent Title: Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
-
Application No.: US16420669Application Date: 2019-05-23
-
Publication No.: US10577337B2Publication Date: 2020-03-03
- Inventor: Jean-Francois Rossignol , Andrew Stachulski
- Applicant: Romark Laboratories, L.C.
- Applicant Address: US FL Tampa
- Assignee: Romark Laboratories, L.C.
- Current Assignee: Romark Laboratories, L.C.
- Current Assignee Address: US FL Tampa
- Agency: Foley & Lardner LLP
- Main IPC: C07D277/46
- IPC: C07D277/46 ; C07D277/58 ; A61K31/138 ; A61K31/506 ; A61K31/555 ; A61K31/704 ; A61K31/7068 ; A61P31/04 ; A61P35/00 ; A61P31/12 ; A61K9/20 ; A61K9/48 ; A61K31/426 ; A61K45/06
Abstract:
Prodrugs of tizoxanide, an analogue or salt thereof are disclosed. The prodrugs have an ester moiety comprising an amino acid moiety, and increase the bioavailability of the tizoxanide, an analogue or salt thereof. Compositions and methods of treating an intracellular protozoan infection, a viral infection or a cancer are also disclosed.
Public/Granted literature
- US20190276417A1 COMPOSITIONS AND METHODS OF TREATMENT WITH PRODRUGS OF TIZOXANIDE, AN ANALOGUE OR SALT THEREOF Public/Granted day:2019-09-12
Information query
