Invention Grant
- Patent Title: Quinolinones as inhibitors of translation initiation complex
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Application No.: US15554419Application Date: 2016-03-01
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Publication No.: US10577349B2Publication Date: 2020-03-03
- Inventor: Ze'ev Ronai , Anthony B. Pinkerton , Yongmei Feng , Ivan Topisirovic , Kevin Brown , Christian A. Hassig
- Applicant: Sanford Burnham Prebys Medical Discovery Institute , The Royal Institution for the Advancement of Learning / McGill University , The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services
- Applicant Address: US CA La Jolla CA Montreal, Quebec US MD Bethesda
- Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE,THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE,THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee Address: US CA La Jolla CA Montreal, Quebec US MD Bethesda
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2016/020273 WO 20160301
- International Announcement: WO2016/140973 WO 20160909
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D401/06
Abstract:
Provided herein are compounds and pharmaceutical compositions comprising quinolinones. The quinolinones and compositions thereof are useful as eukaryotic translation initiation factor 4F (eIF4F) complex modulators.
Public/Granted literature
- US20180044324A1 Quinolinones as Inhibitors of Translation Initiation Complex Public/Granted day:2018-02-15
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