Invention Grant
![5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication](/docs/US/2020-03-03/US10577353B2/abs.jpg.600x600.jpg)
- Patent Title: 5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
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Application No.: US15749144Application Date: 2016-08-10
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Publication No.: US10577353B2Publication Date: 2020-03-03
- Inventor: John F. Kadow , B. Narasimhulu Naidu , Tao Wang , Zhiwei Yin , Zhongxing Zhang
- Applicant: ViiV Healthcare UK (No.5) Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
- Current Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
- Current Assignee Address: GB Brentford, Middlesex
- Agent Robert H. Brink; Kathryn A. Lutomski; Edward R. Gimmi
- International Application: PCT/IB2016/054831 WO 20160810
- International Announcement: WO2017/025916 WO 20170216
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D403/14 ; C07D473/16 ; C07D471/04 ; C07D513/04 ; C07D487/04 ; C07D495/04 ; C07D417/14 ; C07D473/18 ; A61K31/4427 ; A61P31/18 ; A61K31/5365
![5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication](/abs-image/US/2020/03/03/US10577353B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
Public/Granted literature
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