Invention Grant
- Patent Title: Methods for monitoring C9ORF72 expression
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Application No.: US14436039Application Date: 2013-10-15
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Publication No.: US10577604B2Publication Date: 2020-03-03
- Inventor: C. Frank Bennett , Susan M. Freier , Jeffrey D. Rothstein , Christopher Donnelly , Rita G. Sattler
- Applicant: Ionis Pharmaceuticals Inc. , The Johns Hopkins University
- Applicant Address: US CA Carlsbad US MD Baltimore
- Assignee: Ionis Pharmaceuticals, Inc.,The Johns Hopkins University
- Current Assignee: Ionis Pharmaceuticals, Inc.,The Johns Hopkins University
- Current Assignee Address: US CA Carlsbad US MD Baltimore
- Agency: McNeill Baur PLLC
- International Application: PCT/US2013/065131 WO 20131015
- International Announcement: WO2014/062736 WO 20140424
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12Q1/6883 ; A61K31/7088
Abstract:
Disclosed herein are methods for monitoring expression of C9ORF72 mRNA and protein in an animal with C9ORF72 specific inhibitors. Such C9ORF72 specific inhibitors include antisense compounds.
Public/Granted literature
- US20160024496A1 METHODS FOR MONITORING C9ORF72 EXPRESSION Public/Granted day:2016-01-28
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