Invention Grant
- Patent Title: Glypican-3 specific aptamer and use thereof
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Application No.: US15450119Application Date: 2017-03-06
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Publication No.: US10577609B2Publication Date: 2020-03-03
- Inventor: Eun Ju Oh , Jung Hwan Lee , Jong-Hoon Lim , Jong In Kim , Jung Hwan Yoon , Sung Ho Ryu , Jeong-Hoon Lee , Won Jun Kang , Seong Hui Jin
- Applicant: POSTECH ACADEMY—INDUSTRY FOUNDATION
- Applicant Address: KR Pohang-si KR Seoul KR Seoul
- Assignee: POSTECH ACADEMY—INDUSTRY FOUNDATION,SEOUL NATIONAL UNIVERSITY HOSPITAL,YONSEI UNIVERSITY, UNIVERSITY—INDUSTRY FOUNDATION (UIF)
- Current Assignee: POSTECH ACADEMY—INDUSTRY FOUNDATION,SEOUL NATIONAL UNIVERSITY HOSPITAL,YONSEI UNIVERSITY, UNIVERSITY—INDUSTRY FOUNDATION (UIF)
- Current Assignee Address: KR Pohang-si KR Seoul KR Seoul
- Agency: Lex IP Meister, PLLC
- Priority: KR10-2016-0027298 20160307; KR10-2017-0028326 20170306
- Main IPC: C12N15/115
- IPC: C12N15/115 ; C12Q1/68 ; A61K31/7088 ; C12Q1/6886
Abstract:
The present invention relates to a DNA aptamer specifically binding to a hepatocellular carcinoma-related Glypican-3 (GPC3) protein, treatment of cancers related to the Glypican-3 protein using the same, a composition for inhibiting a cancer and a composition for diagnosing a cancer comprising the same as an active ingredient.
Public/Granted literature
- US20190136239A1 GLYPICAN-3 SPECIFIC APTAMER AND USE THEREOF Public/Granted day:2019-05-09
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