Invention Grant
- Patent Title: EpCAM aptamers and conjugates thereof
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Application No.: US15550671Application Date: 2016-02-11
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Publication No.: US10577610B2Publication Date: 2020-03-03
- Inventor: Sarah Shigdar
- Applicant: Deakin University
- Applicant Address: AU Waurun Ponds
- Assignee: Deakin University
- Current Assignee: Deakin University
- Current Assignee Address: AU Waurun Ponds
- Agency: Cesari and McKenna, LLP
- Priority: AU2015900437 20150211
- International Application: PCT/AU2016/050085 WO 20160211
- International Announcement: WO2016/127216 WO 20160818
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/115 ; A61K31/7088 ; A61K48/00
Abstract:
The present disclosure relates to an EpCAM aptamer or an EpCAM aptamer conjugate having bi-functional activity and to uses thereof. In particular, the present disclosure also relates to an aptamer conjugate which binds to the transferrin receptor (TfR) and EpCAM which is useful for treatment of brain tumours and/or brain metastasis.
Public/Granted literature
- US20180037892A1 EPCAM APTAMERS AND CONJUGATES THEREOF Public/Granted day:2018-02-08
Information query
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