Invention Grant
- Patent Title: Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs
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Application No.: US15807034Application Date: 2017-11-08
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Publication No.: US10583199B2Publication Date: 2020-03-10
- Inventor: Jack Henkin , Ignacio Melgar-Asensio
- Applicant: Northwestern University
- Applicant Address: US IL Evanston
- Assignee: Northwestern University
- Current Assignee: Northwestern University
- Current Assignee Address: US IL Evanston
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: A61K47/69
- IPC: A61K47/69 ; C07K7/06 ; A61K9/00 ; C07K14/81 ; C07K14/78 ; C07K14/75 ; C07K14/47 ; A61K47/61 ; A61K47/54 ; A61K38/00

Abstract:
Disclosed are biodegradable nanocarriers that have a net positive surface charge and zeta potential between about +2 to about +20 mV. The positive surface charge of the nanocarriers is provided by peptides that are covalently attached to the surface of the nanocarriers. The nanocarriers may comprise a drug and may be administered for localized and sustained delivery of the drug.
Public/Granted literature
- US20180092988A1 NANOCARRIERS HAVING SURFACE CONJUGATED PEPTIDES AND USES THEREOF FOR SUSTAINED LOCAL RELEASE OF DRUGS Public/Granted day:2018-04-05
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