Invention Grant
- Patent Title: Homologous recombination in multipotent adult progenitor cells
-
Application No.: US15709144Application Date: 2017-09-19
-
Publication No.: US10583202B2Publication Date: 2020-03-10
- Inventor: Catherine M. Verfaillie , Uma Lakshmipathy
- Applicant: ABT Holding Company , Regents of the University of Minnesota
- Applicant Address: US OH Cleveland US MN Minneapolis
- Assignee: ABT Holding Company,Regents of the University of Minnesota
- Current Assignee: ABT Holding Company,Regents of the University of Minnesota
- Current Assignee Address: US OH Cleveland US MN Minneapolis
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: C12N15/85
- IPC: C12N15/85 ; A61K48/00 ; C12N15/10

Abstract:
The invention relates to methods of altering gene expression by homologous recombination in a multipotent adult progenitor cell (MAPC). In particular, methods of producing a recombinant MAPC, of correcting a genetic defect in a mammal, of providing a functional and/or therapeutic protein to a mammal, and of transforming a MAPC are provided. MAPCs containing an erogenous DNA as well as recombinant MAPCs and their differentiated progeny are also provided.
Public/Granted literature
- US20180272000A1 HOMOLOGOUS RECOMBINATION IN MULTIPOTENT ADULT PROGENITOR CELLS Public/Granted day:2018-09-27
Information query
IPC分类: