The present invention includes a line manager to hold and removably secure within an aperture one or more lines or tubes adjacent to a patient on or near a bed rail, body, or other device. In some embodiments, the line manager is attached to a bed rail of a hospital, or medical bed and may be used to position and label the various tubes or lines going to the patient. The line manager may be made of a flexible material and can be a single use device or a multiple use device.