A power-assisted folding knife is provided, including a blade holder, a blade arranged in the blade holder, a handle rotatably connected to the blade holder, a locking mechanism for locking the blade holder in an unfolded position and/or a folded position and a power-assisting mechanism connected to the blade holder and the handle. The power-assisted folding knife uses an assisting mechanism for providing assisting power when unfolding a folding knife, so as to facilitate easier unfolding of the folding knife and to allow single hand operation. Through the locking mechanism, the blade holder can be locked in an unfolded position and/or a folded position to ensure safe use of the power-assisted folding knife.