Disclosed is a sand aerated concrete panel pre-embedded with a wire box and a wire conduit and its preparation method. The concrete panel includes a sand aerated concrete panel, a steel bar mesh cage, a wire box and a wire conduit. The steel bar mesh cage includes a plurality of longitudinal main steel bars, a plurality of transverse auxiliary steel bars and a plurality of connecting iron pieces; the wire box and the wire conduit are fixed on the steel bar mesh cage; and the steel bar mesh cage, the wire box and the wire conduit are poured in the sand aerated concrete panel. The disclosure solves the problems of complicated procedures, high cost, environmental pollution caused by dust and noise in the prior art, avoids the potential quality hazards of the panels and wall structures caused by on-site slotting, reduces labor force, intensity and cost.