A body frame structure that constitutes a side and a top of a vehicle includes: a pillar inner that extends in a vehicle vertical direction on the side of the vehicle; and a rail inner that extends along a boundary line between the side and the top of the vehicle. In an overlapping portion with the pillar inner, the rail inner is formed with a rail bead that is projected to a vehicle outer side. In an overlapping portion with the rail bead, the pillar inner is formed with a pillar bead in such a shape that offsets the rail bead to the vehicle outer side so that the pillar bead is located in a recess of the rail bead.